2-BENZYL-7-(4-CHLOROPHENYL)-3-MORPHOLINO-6-((1-PHENYL-1H-1,2,3-TRIAZOL-4-YL)METHYL)-6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRIDIN-5-ONE

2-Benzyl-7-(4-chlorophenyl)-3-morpholino-6-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one

The new polyheterocyclic compound, 2-benzyl-7-(4-chlorophenyl)-3-morpholino-6-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one, was synthesized by a sequential combination of 4-chlorobenzaldehyde, (1-phenyl-1H-1,2,3-triazol-4-yl)methanamine, 2-isocyano-1-morpholino-3-phenylpropan-1-one, and maleic Pillows anhydrid

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Investigating the current state of the Russian market for drugs treating infectious and inflammatory conditions of oral cavity and oropharynx to demonstrate the need for new drug development

Objective: to assess the relevance and commercial prospects of bringing to market a drug for the local treatment of infectious and inflammatory diseases of oral cavity and oropharynx.Material and methods.The objects of the study were the drug nomenclatures in the State Register of Medicines, the Register of Medicines of Russia, as well as data from

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Psychomotor Retardation in untreated depressed elderly

Background: Psychomotor retardation (PR) is one of the core features in depression according to 17 DSM V1, but also aging in itself causes cognitive and psychomotor slowing.This is the first study 18 investigating psychomotor retardation in relation to cognitive functioning and to the concomitant 19 effect of depression and aging in a geriatric pop

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